Metoclopramide
- Oral / IM / IVMetoclopramideMaxolon, PraminSelectively binds D2 receptors
Mechanism of Action
- Antagonise CNS dopamine receptors, resulting in reduction in nausea and increased upper GI motility.
Clinical Use
- Indications
- Nausea / vomiting
- Gastroparesis
- Adverse Effects
- Restlessness / anxiety / agitation
- Fatigue
- Headache / dizziness
- Diarrhoea
- Dystonic reactions (rare)