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Drug Guide
 
 

Methoxyprogesterone Acetate

 
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    IM
    Methoxyprogesterone Acetate
    Depo-Provera 
     
    Depot injection for 12 weeks of contraception
    Should be given within the first five days of the menstrual cycle
    Causes decreased bone mineral density
  • Mechanism of Action

  • Thickens cervical mucus, resulting in reduced sperm penetration through the cervix. Less of an effect on follicular development and prevention of ovulation than combined contraceptives.

Clinical Use

  • Indications
  • Contraception in patients intolerant of combined oral contraceptives
  • Contraception in women who are breastfeeding
  • Contraindications
  • Pregnancy
  • Past DVT / PE
  • Ischaemic heart disease
  • Past stroke / TIA
  • Breast cancer within the past five years
  • Ischaemic heart disease
  • Adverse Effects
  • Headache
  • Breast pain
  • Nausea / vomiting / bdominal pain
  • Dizziness
  • Depression
  • Irregular bleeding
  • Acne
    Decreased bone mineral density
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