Drug Guide
 

Metformin

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    Oral
    Metformin
    Diabex, Diaformin 
     
    Reduce dose in renal insufficiency
    • Mechanism of Action
    • Inhibits hepatic gluconeogenesis
      Reduces intestinal absorption of glucose
      Stimulates peripheral glucose uptake

Clinical Use

    • Indications
    • Glycaemic control for type II diabetes - first line
    • Gestational diabetes mellitus
    • Polycystic ovarian syndrome (PCOS) with menstrual irregularity
    • Contraindications
    • Renal failure with eGFR <30mL/min.
    • Adverse Effects
    • Nausea / vomiting / diarrhea
    • Lactic acidosis
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