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Drug Guide
 
 

Linezolid

 
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  •  
    Oral / IV
    Linezolid

  • Mechanism of Action

  • Inhibits bacterial protein synthesis by preventing initiation of translation.

  • Microbiology

  • Effective against multi-resistant gram positive organisms, including MRSA, VRE and vancomycin-resistant Staph aureus.

Clinical Use

  • Indications
  • Severe resistant gram positive infections:
  • Pneumonia
  • Septicaemia
  • Skin / soft tissue infections
  • Osteomyelitis / septic arthritis
  • Meningitis
  • Adverse Effects
  • Bone marrow suppression
  • LFT derangement
  • Abnormal taste
  • Nausea / vomiting / diarrhoea
  • Headache
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