- Oral / IVLinezolid
Mechanism of Action
- Inhibits bacterial protein synthesis by preventing initiation of translation.
- Effective against multi-resistant gram positive organisms, including MRSA, VRE and vancomycin-resistant Staph aureus.
- Severe resistant gram positive infections:
- Skin / soft tissue infections
- Osteomyelitis / septic arthritis
- Adverse Effects
- Bone marrow suppression
- LFT derangement
- Abnormal taste
- Nausea / vomiting / diarrhoea