- IV / IMLincomycin
Mechanism of Action
- Inhibits protein synthesis by binding to the 50s ribosomal subunit, resulting in inaccurate mRNA translation.
- Effective against staphylococci, streptococci, pneumococci and most anaerobes.
- Severe gram positive infections:
- Upper / lower respiratory tract infections
- Skin infections
- Osteomyelitis / septic arthritis
- Adverse Effects
- Hypersensitivity reactions
- Nausea / vomiting / diarrhoea
- Elevated LFTs