Lidocaine / Lignocaine / Xylocaine
- Local / Regional / Topical / Nasal / IVLidocaine / Lignocaine / Xylocaine
- Mechanism of Action
- Bind to and inhibit fast sodium channels responsible for rapid depolarisation during phase 0 of the cardiomyocyte action potential.
- Pharmacology
- Weak sodium channel blockade, and decreases the absolute refractory period (ARP).
Clinical Use
- Indications
- Adverse Effects