Levonorgestrel Intra-Uterine Device
- IUSLevonorgestrel Intra-Uterine DeviceMirenaInserted into the uterus for five years of contraception
May cause pelvic inflammatory disease and uterine perforation
Mechanism of Action
- Thickens cervical mucus, resulting in reduced sperm penetration through the cervix. Less of an effect on follicular development and prevention of ovulation than combined contraceptives.
Clinical Use
- Indications
- Contraception in patients intolerant of combined oral contraceptives
- Contraception in women who are breastfeeding
- Contraindications
- Pregnancy
- Past DVT / PE
- Ischaemic heart disease
- Past stroke / TIA
- Breast cancer within the past five years
- Ischaemic heart disease
- Adverse Effects
- Headache
- Breast pain
- Nausea / vomiting / bdominal pain
- Dizziness
- Depression
- Irregular bleeding
- Acne