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Lercanidipine

 
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  •  
    Oral
    Lercanidipine
    Zanidip 

  • Mechanism of Action

  • Inhibits L-type calcium channels on ventricular myocardial, cardiac nodal and arteriolar smooth muscle cells.

  • Pharmacology

  • Selectively inhibits calcium channels on arteriolar smooth muscle cells, resulting in significant vasodilation without cardiodepression.

Clinical Use

  • Indications

  • Hypertension - first line treatment

  • Contraindications

  • Heart failure.
  • Adverse Effects
  • Fatigue
  • Oedema
  • Dizziness
  • Headache
  • Nausea / abdo pain
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