Drug Guide
 

Leflunomide

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    Oral
    Leflunomide
    Arava 
    • Mechanism of Action
    • Believed to inhibit the mitochondrial enzyme dihydroorotate dehydrogenase, which is involved in pyramidine synthesis.

Clinical Use

    • Indications
    • Active rheumatoid arthritis
    • Active psoriatic arthritis
    • Adverse Effects
    • Nausea / vomiting / diarrhoea
    • Rash
    • Hypertension
    • Elevated LFTs
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