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Drug Guide
 
 

Lactulose

 
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    Oral
    Lactulose
    Actilax 
     
    Also used for treatment of hepatic encephalopathy – metabolized by bacteria into D-lactate, reducing gut pH and preventing absorption of ammonia
  • Mechanism of Action

  • An osmotically active agent that draws water into the lumen of the gut.

Clinical Use

  • Indications
  • Constipation
  • Bowel preparation prior to procedures such as colonoscopy (macrogol 3350)
  • Hepatic encephalopathy (lactulose)
  • Adverse Effects
  • Flatulence / diarrhea
  • Nausea / vomiting
  • Electrolyte disturbances
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