Lactulose
- OralLactuloseActilaxAlso used for treatment of hepatic encephalopathy - metabolized by bacteria into D-lactate, reducing gut pH and preventing absorption of ammonia
Mechanism of Action
- An osmotically active agent that draws water into the lumen of the gut.
Clinical Use
- Indications
- Constipation
- Bowel preparation prior to procedures such as colonoscopy (macrogol 3350)
- Hepatic encephalopathy (lactulose)
- Adverse Effects
- Flatulence / diarrhea
- Nausea / vomiting
- Electrolyte disturbances