Topical
Ketoconazole
Nizoral
- Mechanism of Action
- Inhibits fungal synthesis of ergosterol, and element of the fungal cell membrane.
- Microbiology
- Effective against Cryptococcus and Candida.
Clinical Use
- Indications
- Topical - tinea corporis, tinea cruris, tinea manus, tinea pedis
- Systemic – cryptococcal meningitis, candidiasis
- Adverse Effects
- With systemic use only:
- Rash
- Nausea / vomiting / diarrhoea
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