×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Ketamine

 
Bookmark
  •  
    IV
    Ketamine
    Ketalar 
  • Mechanism of Action
  • Acts as a non-competitive antaagonist at the NMDA receptor
  • Reduces presynaptic release of glutamate
  • Agonises α and β adrenoceptors
  • Agonises opioid σ receptors

Clinical Use

  • Indications
  • Analgesia
  • General anaesthesia for procedures not requiring muscle relaxant
  • Induction of anaesthesia in conjunction with other agents
  • Contraindications
  • Severe cardiovascular disease – heart failure, poorly controlled hypertension, recent MI
  • Past stroke / brain tumour / intracerebral haemorrhage
  • Adverse Effects
  • Tachycardia
  • Hypertension
  • Diplopia / nystagmus
  • Raised intracranial pressure
  • Nausea / vomiting / anorexia
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...