MedSchool: Ace Your OSCEsThe Medical Company
GET - On the App Store
Drug Guide

Isosorbide Mononitrate (ISMN)

    Isosorbide Mononitrate (ISMN)
    Imdur, Duride 
    Long-acting, to be used to control stable angina pectoris
    • Mechanism of Action
    • Converted to nitrous oxide which stimulates vascular smooth muscle relaxation through stimulation of cGMP-dependant protein kinase with resultant reduction in intracellular calcium.
      Results in venous dilatation (reduced preload), arterial dilatation (reduced afterload) and coronary dilatation (improved myocardial oxygen supply)
    • Pharmacology
    • Long-acting

Clinical Use

    • Indication
    • Stable angina pectoris
    • Adverse Effects
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now