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Isophane Insulin

 
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    Isophane Insulin
    Protaphane, Humulin NPH 
  • Mechanism of Action

  • Insulin is an hormone normally produced by pancreatic beta cells that is responsible for regulation of glucose, fat and protein metabolism.
  • Pharmacology
  • Cloudy solution - prepare using 'rock 'n roll' technique
  • Onset 90 minutes
  • Peak effect 4-12 hours
  • Duration 24 hours

Clinical Use

  • Indications

  • Generally used as part of a combination insulin formulation.
  • Contraindications

  • Hypoglycaemia.
  • Adverse Effects
  • Hypoglycaemia
  • Weight gain
  • Hypersensitivity reactions
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