Isophane Insulin

• Mechanism of Action
• Insulin is an hormone normally produced by pancreatic beta cells that is responsible for regulation of glucose, fat and protein metabolism.
• • Pharmacology
  • Cloudy solution - prepare using 'rock ‘n roll' technique
  • Onset 90 minutes
  • Peak effect 4-12 hours
  • Duration 24 hours

Clinical Use

• • Indication
  • Generally used as part of a combination insulin formulation.
• • Contraindications
  • Hypoglycaemia.
• • Adverse Effects
  • Hypoglycaemia
  • Weight gain
  • Hypersensitivity reactions