Isophane Insulin
- SubcutIsophane InsulinProtaphane, Humulin NPH
Mechanism of Action
- Insulin is an hormone normally produced by pancreatic beta cells that is responsible for regulation of glucose, fat and protein metabolism.
- Pharmacology
- Cloudy solution - prepare using 'rock ‘n roll' technique
- Onset 90 minutes
- Peak effect 4-12 hours
- Duration 24 hours
Clinical Use
Indications
- Generally used as part of a combination insulin formulation.
Contraindications
- Hypoglycaemia.
- Adverse Effects
- Hypoglycaemia
- Weight gain
- Hypersensitivity reactions