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Irbesartan

  •  
    Oral
    Irbesartan
    Avapro, Karvea 
    • Mechanism of Action
    • Competitively inhibits the action of angiotensin II at AT1 receptors.

Clinical Use

    • Indications
    • Hypertension – first line management, especially in patients with chronic kidney disease (CKD)
    • Heart failure
    • Diabetic nephropathy
    • Contraindications
    • Severe renal impairment
    • Severe hepatic impairment
    • Patients on direct renin inhibitors (aliskiren)
    • Adverse Effects
    • Nausea / vomiting / diarrhoea
    • Fatigue
    • Oedema
    • Upper respiratory tract infection

Potential Indications
BETA

Essential Hypertension
Heart Failure with Reduced Ejection Fraction
Chronic Kidney Disease
Diabetic Nephropathy
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