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Drug Guide
 
 

Insulin Glargine

 
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    Subcut
    Insulin Glargine
    Lantus, Toujeo 
     
    Once daily dosing
  • Mechanism of Action

  • Insulin is an hormone normally produced by pancreatic beta cells that is responsible for regulation of glucose, fat and protein metabolism.
  • Pharmacology
  • Clear solution
  • Onset 1-3 hours
  • No peak
  • Duration <24 hours (Levemir) / >24 hours (Lantus)
  • Tend to suppress hepatic gluconeogenesis, preventing hyperglycaemia in fasting conditions
  • Prevent ketogenesis

Clinical Use

  • Indications

  • Basal insulin for hyperglycaemic control over 24 hours, either alone or in combination with bolus dosing.
  • Contraindications

  • Hypoglycaemia.
  • Adverse Effects
  • Hypoglycaemia
  • Weight gain
  • Hypersensitivity reactions
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