Subcut
Insulin Detemir
Levemir
- Mechanism of Action
- Insulin is an hormone normally produced by pancreatic beta cells that is responsible for regulation of glucose, fat and protein metabolism.
- Pharmacology
- Clear solution
- Onset 1-3 hours
- No peak
- Duration <24 hours (Levemir) / >24 hours (Lantus)
- Tend to suppress hepatic gluconeogenesis, preventing hyperglycaemia in fasting conditions
- Prevent ketogenesis
Clinical Use
- Indication
- Basal insulin for hyperglycaemic control over 24 hours, either alone or in combination with bolus dosing.
- Contraindications
- Hypoglycaemia.
- Adverse Effects
- Hypoglycaemia
- Weight gain
- Hypersensitivity reactions
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