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Indacaterol

 
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    MDI
    Indacaterol
    Onbrez 

  • Mechanism of Action

  • Directly binds to airway β2 adrenoceptors, stimulating smooth muscle relaxation and bronchodilation through induction of cAMP with resulting phosphorylation of muscle regulatory proteins and modification of cellular calcium concentration.

Clinical Use

  • Indications

  • COPD maintenance therapy.
  • Adverse Effects
  • Tremor
  • Palpitations
  • Hypokalaemia / hypomagnesaemia
  • Ketoacidosis (diabetics)
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