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Drug Guide
 
 

Hydromorphone

 
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  •  
    Oral / IV / Subcut
    Hydromorphone
    Dilaudid (IR), Jurnista (SR) 
     
    Able to be used in renal dysfunction
    • Mechanism of Action
    • Act on opioid receptors (δ, κ and µ) and nociceptin orphanin FQ (NOF) receptors on neuronal cell membranes within the thalamus, diencephalon, midbrain and medulla, resulting in reduced neurotransmitter release.
    • Pharmacology
    • Less histamine release (flushing, itching, rash) and less constipating than natural opioids.

Clinical Use

    • Indications
    • Adverse Effects
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