Hydralazine
- Oral / IVHydralazineAlphapress
Mechanism of Action
- Relaxes vascular smooth muscle (predominantly arterioles) through opening of potassium channels, resulting in reduced afterload.
Clinical Use
- Indications
- Hypertensive crisis (IV)
- Refractory hypertension (oral)
- Adverse Effects
- Headache
- Flushing
- Nausea / vomiting / diarrhoea
- Tachycardia / palpitations
- Arthralgia / myalgia