• Mechanism of Action
• Inhibits tumour necrosis factor alpha (TNF-α), a cytokine involved in systemic inflammation and the acute phase response.

Clinical Use

• • Indications
  • Moderate to severe rheumatoid arthritis
  • Psoriatic arthritis
  • Ankylosing spondylitis
  • Severe refractory ulcerative colitis
• • Adverse Effects
  • Severe infections
  • Reactivation of tuberculosis
  • Anaemia
  • Headache
  • Nausea / diarrhoea
  • Exacerbation of congestive cardiac failure
  • Demyelinating disease