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Golimumab

  •  
    Subcut
    Golimumab
    Simponi 
     
    Human monoclonal antibody to TNF
    • Mechanism of Action
    • Inhibits tumour necrosis factor alpha (TNF-α), a cytokine involved in systemic inflammation and the acute phase response.

Clinical Use

    • Indications
    • Moderate to severe rheumatoid arthritis
    • Psoriatic arthritis
    • Ankylosing spondylitis
    • Severe refractory ulcerative colitis
    • Adverse Effects
    • Severe infections
    • Reactivation of tuberculosis
    • Anaemia
    • Headache
    • Nausea / diarrhoea
    • Exacerbation of congestive cardiac failure
    • Demyelinating disease

Potential Indications
BETA

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