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Drug Guide
 
 

Glimepiride

 
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    Oral
    Glimepiride
    Amaryl 
  • Mechanism of Action

  • Inhibits potassium channels on pancreatic beta cell membranes, resulting in calcium influx and thus insulin release.

Clinical Use

  • Indications

  • Glycaemic control for type II diabetes - second line
  • Adverse Effects
  • Hypoglycaemia
  • Nausea / vomiting / diarrhea
  • Thrombocytopaenia / leukopaenia / haemolytic anaemia
  • Weight gain
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