Drug Guide
 

Ganciclovir

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    IV, intravitreal
    Ganciclovir

    • Mechanism of Action
    • An analogue of the nucleoside guanosine that is incorporated into viral DNA by viral DNA polymerase, resulting in premature DNA termination.
    • Microbiology
    • Effective against Herpes simplex virus (HSV), varicella zoster virus (VZV) and cytomegalovirus (CMV).

Clinical Use

    • Indications
    • Treatment / prophylaxis for CMV infection in immunocompromised patients
    • Genital herpes
    • Cold sores
    • Herpes simplex encephalitis
    • Chickenpox (in adults)
    • Shingles
    • Ophthalmic herpes zoster
    • Adverse Effects
    • Nausea / vomiting, headache.
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