Mechanism of Action
- Not fully described, though believed to modulate GABA synthesis. Also binds to the α2δ-1 subunit of voltage-gated calcium channels, resulting in reduced nociceptive neurotransmission.
Clinical Use
- Indications
- Partial seizures
- Neuropathic pain
- Adverse Effects
- Fatigue
- Weight gain
- Dizziness / ataxia
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