Fulvestrant
- IMFulvestrantFaslodexMonthly injections
Mechanism of Action
- Antagonises oestrogen receptors without agonist activity.
Clinical Use
Indications
- Hormone receptor positive, locally advanced or metastatic breast cancer that does not respond to tamoxifen.
- Adverse Effects
- Elevated LFTs
- Nausea / vomiting / diarrhoea
- Hot flushes
- Headache