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Drug Guide
 
 

Foscarnet

 
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    IV
    Foscarnet
    Foscavir 
    • Mechanism of Action

    • Directly inhibits the pyrophosphate binding sites of viral DNA polymerase, resulting in premature DNA termination.
    • Microbiology

    • Broad spectrum of activity against HSV1/2, VZV, CMV, hepatitis B and HIV.

Clinical Use

    • Indications
    • Treatment of CMV retinitis in patients with AIDS
    • Aciclovir-resistant herpes simplex virus (HSV) infections
    • Adverse Effects
    • Rash
    • Headache
    • Nausea / vomiting / diarrhoea
    • Neutropaenia / anaemia
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