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Drug Guide
 
 

Foscarnet

 
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    IV
    Foscarnet
    Foscavir 
  • Mechanism of Action

  • Directly inhibits the pyrophosphate binding sites of viral DNA polymerase, resulting in premature DNA termination.
  • Microbiology

  • Broad spectrum of activity against HSV1/2, VZV, CMV, hepatitis B and HIV.

Clinical Use

  • Indications
  • Treatment of CMV retinitis in patients with AIDS
  • Aciclovir-resistant herpes simplex virus (HSV) infections
  • Adverse Effects
  • Rash
  • Headache
  • Nausea / vomiting / diarrhoea
  • Neutropaenia / anaemia
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