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Drug Guide
 
 

Fomepizole

 
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  •  
    IV
    Fomepizole
    Antizol 

  • Mechanism of Action

  • Directly inhibits ADH, which metabolizes methanol and ethylene glycol into toxic metabolites formic acid and glycolic acid respectively.

  • Pharmacology

  • Higher affinity for ADH than ethanol.

Clinical Use

  • Indications

  • Methanol or ethylene glycol poisoning.
  • Adverse Effects
  • Headache
  • Nausea / vomiting
  • Dizziness
  • Drowsiness
  • Metallic taste
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