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Flutamide

  •  
    Oral
    Flutamide

    • Mechanism of Action
    • Directly inhibits the binding of androgens to androgen receptors.
    • Pharmacology
    •  Interacts only with androgen receptors, producing no progestin or glucocorticoid effects.

Clinical Use

    • Indication
    • Androgen deprivation therapy for metastatic castrate-resistant prostate cancer.
    • Contraindications
    • Seizure disorders.
    • Adverse Effects
    • Nausea / vomiting / diarrhoea
    • Gynaecomastia / breast tenderness
    • Hot flushes
    • Dizziness
    • Elevated LFTs
    • Osteoporosis (long-term)

Potential Indications
BETA

Prostate Cancer

Associated Adverse Effects
BETA

Osteoporosis
Osteoporosis
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