Flupenthixol
- IMFlupenthixolDepot – fortnightly / monthly dosing for schizophrenia
- Mechanism of Action
- Inhibits dopamine D2 receptors, resulting in reduced dopaminergic transmission within the four dopaminergic pathways. Also inhibits serotonin (5-HT), muscarinic and α1-adrenergic receptors.
- Pharmacology
- More extrapyramidal side effects than atypical antipsychotics.
Clinical Use
- Indications
- Adverse Effects