Fluconazole
- Oral / IVFluconazoleDiflucan
Mechanism of Action
- Inhibits fungal synthesis of ergosterol, and element of the fungal cell membrane.
Microbiology
- Effective against Cryptococcus and Candida.
Clinical Use
- Indications
- Cryptococcal meningitis
- Invasive candidiasis
- Adverse Effects
- With systemic use only:
- Rash
- Nausea / vomiting / diarrhoea