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Flecainide

 
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  •  
    Oral / IV
    Flecainide

  • Mechanism of Action

  • Binds to and inhibits fast sodium channels responsible for rapid depolarisation during phase 0 of the cardiomyocyte action potential.

Clinical Use

  • Indications
  • Prophylaxis of paroxysmal supraventricular tachycardia
  • Acute management of ventricular tachycardia
  • Adverse Effects
  • Dizziness / headache / visual changes
  • Ventricular arrhythmias – VT / VF
  • Bradyarrhythmia – sinus bradycardia, heart block
  • Heart failure
  • Dyspnoea
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