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Fingolimod

 
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 View Topic Outline
  •  
    Oral
    Fingolimod
    Gilenya 

  • Mechanism of Action

  • Inhibits the release of T cells from lymph nodes, resulting in redistribution of T cells and decreased entry into the central nervous system.

Clinical Use

  • Indications
  • Relapsing-remitting multiple sclerosis
  • Secondary progressive multiple sclerosis
  • Contraindications
  • Other immunomodulatory agents
  • Immunocompromised patients
  • Adverse Effects
  • Headache
  • Elevated LFTs
  • Diarrhoea
  • Upper respiratory tract infection
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