×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Fentanyl

 
Bookmark
  •  
    Oral / IV / IM / Subcut / Topical / Epidural
    Fentanyl
    Durogesic patch 
     
    Strong µ receptor selectivity
    Short duration of action, though patches create a reservoir in the skin
  • Mechanism of Action

  • Acts on opioid receptors (δ, κ and µ) and nociceptin orphanin FQ (NOF) receptors on neuronal cell membranes within the thalamus, diencephalon, midbrain and medulla, resulting in reduced neurotransmitter release.

Clinical Use

  • Indications

  • Acute and chronic pain
  • Adverse Effects
  • Nausea / vomiting
  • Constipation
  • Sedation
  • Respiratory depression
  • Diaphoresis
  • Delirium
  • Hypersensitivity – bronchospasm, urticaria
  • Bradycardia
  • Tolerance
  • Dependence
  • Hypogonadism
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...