- Oral / IV / IM / Subcut / Topical / EpiduralFentanylDurogesic patchStrong µ receptor selectivity
Short duration of action, though patches create a reservoir in the skin
- Mechanism of Action
- Acts on opioid receptors (δ, κ and µ) and nociceptin orphanin FQ (NOF) receptors on neuronal cell membranes within the thalamus, diencephalon, midbrain and medulla, resulting in reduced neurotransmitter release.
- Acute and chronic pain
- Adverse Effects