Famciclovir
- OralFamciclovir77% bioavailability
Mechanism of Action
- A nucleoside analogue that is incorporated into viral DNA by viral DNA polymerase, resulting in premature DNA termination.
Microbiology
- Effective against Herpes simplex virus (HSV), varicella zoster virus (VZV) and cytomegalovirus (CMV).
Clinical Use
- Indications
- Genital herpes
- Cold sores
- Herpes simplex encephalitis
- Chickenpox (in adults)
- Shingles
- Ophthalmic herpes zoster
Adverse Effects
- Nausea / vomiting, headache.