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Exenatide

  •  
    Subcut
    Exenatide
    Byetta (daily), Bydureon (weekly) 
    • Mechanism of Action
    • Directly agonises GLP-1 receptors, resulting in glucose-dependant insulin secretion.
    • Pharmacology
    • Stimulates insulin secretion in hyperglycaemia, and Inhibits glucagon secretion in hyperglucagonaemia.
    • Also results in delayed gastric emptying, appetite suppression and weight loss.

Clinical Use

    • Indications
    • Glycaemic control for type II diabetesGlycaemic control for type II diabetics
    • Adjunctive therapy for weight loss
    • Adverse Effects
    • URTI
    • Headache
    • PancreatitisHypoglycaemia
    • Headache
    • Reflux
    • Nausea / vomiting
    • Pancreatitis

Potential Indications
BETA

Type 2 Diabetes

Associated Adverse Effects
BETA

Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease
Acute Pancreatitis
Acute Pancreatitis
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