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Drug Guide
 
 

Exenatide

 
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  •  
    Subcut
    Exenatide
    Byetta (daily), Bydureon (weekly) 

  • Mechanism of Action

  • Directly agonises GLP-1 receptors, resulting in glucose-dependant insulin secretion.
  • Pharmacology
  • Stimulates insulin secretion in hyperglycaemia, and Inhibits glucagon secretion in hyperglucagonaemia.
  • Also results in delayed gastric emptying, appetite suppression and weight loss.

Clinical Use

  • Indications
  • Glycaemic control for type II diabetesGlycaemic control for type II diabetics
  • Adjunctive therapy for weight loss
  • Adverse Effects
  • URTI
  • Headache
  • PancreatitisHypoglycaemia
  • Headache
  • Reflux
  • Nausea / vomiting
  • Pancreatitis
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