Login or Register to unlock everything MedSchool has to offer!
Full Drug List
 

#

A

B

C

D

E

F

G

H

I

K

N

O

P

Q

R

S

T

U

V

W

Z

 
 

Everolimus

  •  
    Oral
    Everolimus
    Certican 
     
    Half-life ~30 hours
    • Mechanism of Action
    • Forms a complex with FKBP-12 to inhibit mTOR, a key regulatory protein, and induces cell cycle arrest of T cells, B cells and other non-immune cells.

Clinical Use

    • Indications
    • Prevention of graft rejection following kidney, liver or heart transplantation
    • Adverse Effects
    • Pancytopaenia
    • Infections (particularly respiratory and urinary tract)
    • Poor wound healing
    • Mouth ulcers
    • Male hypogonadism
    • Dyslipidaemia
    • Insomnia
    • Anxiety
    • Headache

Associated Adverse Effects
BETA

Sleep Disorders
Feedback