×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Everolimus

 
Bookmark
 View Topic Outline
  •  
    Oral
    Everolimus
    Certican 
     
    Half-life ~30 hours

  • Mechanism of Action

  • Forms a complex with FKBP-12 to inhibit mTOR, a key regulatory protein, and induces cell cycle arrest of T cells, B cells and other non-immune cells.

Clinical Use

  • Indications
  • Prevention of graft rejection following kidney, liver or heart transplantation
  • Adverse Effects
  • Pancytopaenia
  • Infections (particularly respiratory and urinary tract)
  • Poor wound healing
  • Mouth ulcers
  • Male hypogonadism
  • Dyslipidaemia
  • Insomnia
  • Anxiety
  • Headache
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...