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Etoposide

  •  
    IV
    Etoposide

    • Mechanism of Action
    • Causes DNA strand breakage through inhibition of topoisomerase II.

Clinical Use

    • Indication
    • Certain solid organ and haematologic organ malignancies, as guided by cancer specialists and local guidelines.
    • Adverse Effects
    • Bone marrow suppression – leucopaenia, thrombocytopaenia, anaemia
    • Nausea / vomiting / anorexia
    • Fever
    • Alopecia
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