Etoposide
- IVEtoposide
Mechanism of Action
- Causes DNA strand breakage through inhibition of topoisomerase II.
Clinical Use
Indications
- Certain solid organ and haematologic organ malignancies, as guided by cancer specialists and local guidelines.
- Adverse Effects
- Bone marrow suppression – leucopaenia, thrombocytopaenia, anaemia
- Nausea / vomiting / anorexia
- Fever
- Alopecia