Ethosuxamide
- OralEthosuxamideZarontin
Mechanism of Action
- Inhibits T-type calcium channels in the thalamus, preventing propagation of action potentials and thus suppressing seizure activity
Clinical Use
Indications
- Absence seizures.
- Adverse Effects
- Nausea / vomiting
- CNS disturbances - drowsiness, headache, ataxia