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Drug Guide
 
 

Esomeprazole

 
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 View Topic Outline
  •  
    Oral / IV
    Esomeprazole
    Nexium 

  • Mechanism of Action

  • Inhibits H⁺ / K⁺ ATPase, the channel responsible for pumping gastric acid into the lumen.

  • Pharmacology

  • A prodrug that requires gastric acid in order to be activated.

Clinical Use

  • Indications
  • Gastro-oesophageal reflux disease
  • Peptic ulceration
  • Zollinger-Ellison syndrome
  • Adverse Effects
  • Headache
  • Nausea / vomiting / diarrhea
  • Hypomagnesaemia
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