Drug Guide


    IV / IM

    • Mechanism of Action
    • Stimulates contraction of uterine and vascular smooth muscle, through agonism of alpha-adrenergic, dopaminergic and serotonin (5-HT) receptors.

Clinical Use

    • Indications
    • Induction of labour
    • Augmentation of labour
    • Management of the third stage of labour
    • Postpartum haemorrhage Prevention and management of postpartum haemorrhage after delivery of the placenta.
    • Contraindications
    • Suspected retained placenta
    • Severe hypertension / eclampsia / preeclampsia
    • Peripheral vascular disease / ischaemic heart disease
    • Adverse Effects
    • Headache
    • Nausea / vomiting / diarrhoea
    • Coronary artery spasm
    • Hypertension
    • Gangrene
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