×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Enzalutamide

 
Bookmark
 View Topic Outline
  •  
    Oral
    Enzalutamide
    Xtandi 

  • Mechanism of Action

  • Directly inhibits the binding of androgens to androgen receptors.

  • Pharmacology

  •  Interacts only with androgen receptors, producing no progestin or glucocorticoid effects.

Clinical Use

  • Indications

  • Androgen deprivation therapy for metastatic castrate-resistant prostate cancer.

  • Contraindications

  • Seizure disorders.
  • Adverse Effects
  • Nausea / vomiting / diarrhoea
  • Gynaecomastia / breast tenderness
  • Hot flushes
  • Dizziness
  • Elevated LFTs
  • Osteoporosis (long-term)
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...