Mechanism of Action
- Directly inhibits the binding of androgens to androgen receptors.
- Interacts only with androgen receptors, producing no progestin or glucocorticoid effects.
- Androgen deprivation therapy for metastatic castrate-resistant prostate cancer.
- Seizure disorders.
- Adverse Effects
- Nausea / vomiting / diarrhoea
- Gynaecomastia / breast tenderness
- Hot flushes
- Elevated LFTs
- Osteoporosis (long-term)