Login or Register to unlock everything MedSchool has to offer!
Full Drug List
 

#

A

B

C

D

E

F

G

H

I

K

N

O

P

Q

R

S

T

U

V

W

Z

 
 

Duloxetine

  •  
    Oral
    Duloxetine
    Cymbalta 
     
    Primarily inhibits noradrenaline reuptake
    • Mechanism of Action
    • Inhibits presynaptic reuptake of both serotonin and norepinephrine, resulting in greater concentrations within the synapse.

Clinical Use

    • Indications
    • Depression
    • Generalised anxiety disorder
    • Contraindications
    • Not for concurrent use with monoamine oxidase inhibitors (MAOi).
    • Adverse Effects
    • Fatigue
    • Insomnia
    • Dry mouth
    • Weight loss / gain
    • Dizziness / headache
    • Nausea / vomiting / diarrhea
    • Sexual dysfunction – decreased libido, ejaculatory disorders, erectile dysfunction
    • Serotonin syndrome (when SNRIs given with MAOis / SSRIs) – confusion, agitation, ataxia, hyperreflexia, fevers, diaphoresis

Potential Indications
BETA

Associated Adverse Effects
BETA

Sleep Disorders
Feedback