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Drug Guide
 
 

Doxorubicin

 
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    IV
    Doxorubicin
    Adriamycin 
  • Mechanism of Action

  • Inserted between DNA base pairs, resulting in inhibition of topoisomerase II.

Clinical Use

  • Indications

  • Certain solid organ and haematologic organ malignancies, as guided by cancer specialists and local guidelines.
  • Adverse Effects
  • Bone marrow suppression – leucopaenia / anaemia / thrombocytopaenia
  • Cardiomyopathy / congestive cardiac failure
  • Nausea / vomiting / diarrhoea / anorexia
  • Stomatitis
  • Alopecia
  • Rash
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