×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Doxepin

 
Bookmark
 View Topic Outline
  •  
    Oral
    Doxepin
    Deptran 

  • Mechanism of Action

  • Blocks presynaptic reuptake of serotonin (5-HT) and noradrenaline (NA) through an unknown mechanism.

Clinical Use

  • Indications
  • Depression
  • Fibromyalgia
  • Migraine prophylaxis
  • Neuropathic pain
  • Post-traumatic stress disorder (PTSD)

  • Contraindications

  • Not for concurrent use with monoamine oxidase inhibitors (MAOi).
  • Adverse Effects
  • Nausea / vomiting / diarrhea
  • Adrenergic - postural hypotension
  • Histaminic - sedation, weight gain
  • Anticholinergic - dry mouth, blurred vision, constipation, urinary retention
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now
   
 
 

Snapshot: Initialising...