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Domperidone

  •  
    Oral
    Domperidone
    Motilium 
     
    Binds D2 and D3 receptors; doesn’t cross the BBB
    • Mechanism of Action
    • Antagonise CNS dopamine receptors, resulting in reduction in nausea and increased upper GI motility.

Clinical Use

    • Indications
    • Nausea / vomiting
    • Gastroparesis
    • Adverse Effects
    • Restlessness / anxiety / agitation
    • Fatigue
    • Headache / dizziness
    • Diarrhoea
    • Dystonic reactions (rare)

Potential Indications
BETA

Associated Adverse Effects
BETA

Extrapyramidal & Movement Disorders
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