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Drug Guide
 
 

Dipyridamole

 
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  •  
    Oral / IV
    Dipyridamole
    Persantin 

  • Mechanism of Action

  • Inhibits platelet cAMP-phosphodiesterase, preventing platelet aggregation. Also augments the platelet inhibitory effect of adenosine by preventing reuptake and degradation of adenosine by endothelial and red blood cells.

Clinical Use

  • Indications
  • Secondary prevention of stroke (in combination with aspirin)
  • Prevention of thromboembolism post prosthetic heart valve surgery (in combination with anticoagulants)
  • Adverse Effects
  • Nausea / vomiting / diarrhoea
  • Headache / dizziness
  • Vasodilation - flushing, hypotension
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