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Drug Guide
 
 

Digoxin

 
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    IV / Oral
    Digoxin
    Lanoxin 
    • Mechanism of Action
    • Inhibits Na⁺ / K⁺ ATPase, causing sodium influx which results in calcium influx through reduced action of the Na⁺ / Ca²⁺ exchange pump.
      Increases contractility (positive inotropy) and decreases heart rate (negative chronotropy).
    • Pharmacology
    • Takes 5-7 days to achieve a therapeutic effect.

Clinical Use

    • Indications
    • Adverse Effects
    • Monitoring
    • Has a narrow therapeutic index, thus levels must be monitored regularly.
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