Drug Guide
 

Diazepam

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    Oral / IV / IM
    Diazepam
    Valium 
     
    [Peak] 1-2 hours
    Half-life 20-48 hours
    • Mechanism of Action
    • Positively modulates GABAA receptors (BZ1 and BZ2), augmenting the inhibitory effects of the GABA neurotransmitter.

Clinical Use

    • Indications
    • Acute anxiety
    • Tranquilization – in the acute psychiatric setting
    • Withdrawal – from alcohol, benzodiazepines, opioids
    • Status epilepticus
    • Adverse Effects
    • Drowsiness
    • Hypersalivation
    • Muscle weakness
    • Vertigo
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