×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Desvenlafaxine

 
Bookmark
  •  
    Oral
    Desvenlafaxine
    Pristiq 
     
    Some additional inhibition of dopamine reuptake
  • Mechanism of Action

  • Inhibits presynaptic reuptake of both serotonin and norepinephrine, resulting in greater concentrations within the synapse.

Clinical Use

  • Indications

  • Depression
  • Contraindications

  • Not for concurrent use with monoamine oxidase inhibitors (MAOi).
  • Adverse Effects
  • Fatigue
  • Insomnia
  • Dry mouth
  • Weight loss / gain
  • Dizziness / headache
  • Nausea / vomiting / diarrhea
  • Sexual dysfunction – decreased libido, ejaculatory disorders, erectile dysfunction
  • Serotonin syndrome (when SNRIs given with MAOis / SSRIs) – confusion, agitation, ataxia, hyperreflexia, fevers, diaphoresis
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now