Drug Guide
 

Desvenlafaxine

Bookmark
  •  
    Oral
    Desvenlafaxine
    Pristiq 
     
    Some additional inhibition of dopamine reuptake
    • Mechanism of Action
    • Inhibits presynaptic reuptake of both serotonin and norepinephrine, resulting in greater concentrations within the synapse.

Clinical Use

    • Indication
    • Depression
    • Contraindications
    • Not for concurrent use with monoamine oxidase inhibitors (MAOi).
    • Adverse Effects
    • Fatigue
    • Insomnia
    • Dry mouth
    • Weight loss / gain
    • Dizziness / headache
    • Nausea / vomiting / diarrhea
    • Sexual dysfunction – decreased libido, ejaculatory disorders, erectile dysfunction
    • Serotonin syndrome (when SNRIs given with MAOis / SSRIs) – confusion, agitation, ataxia, hyperreflexia, fevers, diaphoresis
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Explore
   
 
Feedback