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Drug Guide
 
 

Dacarbazine

 
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  •  
    IV
    Dacarbazine

  • Mechanism of Action

  • Creates DNA adducts that cause base-base mismatches and DNA instability.

Clinical Use

  • Indications

  • Certain solid organ and haematologic organ malignancies, as guided by cancer specialists and local guidelines.
  • Adverse Effects
  • Bone marrow suppression – leucopaenia, anaemia, thrombocytopaenia
  • Nausea / vomiting / diarrhoea
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