×
MedSchool: Ace Your OSCEsThe Medical Company
 
 
 
 
 
GET - On the App Store
View
Drug Guide
 
 

Dacarbazine

 
Bookmark
 View Topic Outline
  •  
    IV
    Dacarbazine

  • Mechanism of Action

  • Creates DNA adducts that cause base-base mismatches and DNA instability.

Clinical Use

  • Indications

  • Certain solid organ and haematologic organ malignancies, as guided by cancer specialists and local guidelines.
  • Adverse Effects
  • Bone marrow suppression – leucopaenia, anaemia, thrombocytopaenia
  • Nausea / vomiting / diarrhoea
Want more info like this?
  • Your electronic clinical medicine handbook
  • Guides to help pass your exams
  • Tools every medical student needs
  • Quick diagrams to have the answers, fast
  • Quizzes to test your knowledge
Sign Up Now